Vaccinia Virus and Poxvirology: Methods and Protocols

Product Details
»Book Publisher: Humana Press (19 April, 2004)
»ISBN: 1588292290
»Book author: Stuart N. Isaacs
»Amazon Rating:
Book De******ion:
A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene tran******ions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene tran******ion and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.