Protein Degradation: The Ubiquitin-Proteasome System and Disease

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Protein Degradation: The Ubiquitin-Proteasome System and Disease (Protein Degradation)
By R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner


Publisher: Wiley-VCH
Number Of Pages: 258
Publication Date: 2007-12-19
ISBN-10 / ASIN: 3527314369
ISBN-13 / EAN: 9783527314362
Binding: Hardcover


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This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease.

The editors and authors represent unmatched expertise, comprising virtually all the top scientists in the field, including the pioneers of protein degradation research.

From the contents:

Ubiquitin and cancer
Ubiquitin and liver cancer
Muscle atrophy
Aggresomes and human disease
Parkin and neurodegeneration
Chronic neurodegenerative diseases
Parkinson's disease
Ubiquitin and viruses
Druggability of the ubiquitin-proteasome system
Required reading for molecular and cell biologists, as well as physiologists with an interest in the topic.


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